The Dynamics of Virus and Rickettsial Infections. International Symposium. COPY OF NOBEL LAUREATE THOMAS H. WELLER. - Rare Book Insider
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The Dynamics of Virus and Rickettsial Infections. International Symposium. COPY OF NOBEL LAUREATE THOMAS H. WELLER.

xii, 461 pp; text figures. Original cloth. Top & bottom of spine rubbed, with small tear at top of spine. Good. First Edition. COPY OF NOBEL LAUREATE THOMAS H. WELLER, with his printed name and the date (3/19/54) on the front flyleaf. This book was published in the same year (1954) that John Enders, Thomas Weller, and Frederick Robbins shared the Nobel Prize in Physiology or Medicine "for their discovery of the ability of poliomyelitis viruses to grow in cultures of various types of tissue." Weller's paper is "The Diagnosis of Viral Infections Employing Tissue Culture Methods" (pp. 334-347). John Enders, Thomas Weller, and Frederick Robbins shared the Nobel Prize in Physiology or Medicine in 1954 "for their discovery of the ability of poliomyelitis viruses to grow in cultures of various types of tissue." "The Symposium was sponsored by the Henry Ford Hospital, Detroit, Michigan and held at the Hospital October 21, 22 and 23, 1953." Among the many eminent contributors to the Symposium are: Nobel laureates in 1969 A. D. Hershey and S. E. Luria; and the polio vaccine creators Jonas E. Salk and Albert B. Sabin.
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Classical Theory of Radiating Electrons.” Reprinted from Proceedings of the Royal Society of London, Series A. No. 929, Vol. 167, August 1938, pp. 148-69.

Pp. 148-69. Original wrappers. Near Fine. First Edition. Author's offprint. "Dirac's scientific work often dealt with subjects that were far from mainstream physics. Typically for such an original mind, he preferred to cultivate new subjects according to his own tastes. He never cared about fashions of the physics community and accepted his self-chosen isolation. One example is his work on the classical theory of the electron, which started in 1938. . . . His paper of 1938 was an important contribution to electron theory and is still considered to be a classic. . . . Dirac was very dissatisfied with the state of the art in quantum electrodynamics and desperately searched of new ways to get rise of the infinities that plagued the theory. One strategy toward that end was to base quantum electrodynamics on an improved classical theory. This strategy had been considered earlier, for example, by Oppenheimer. . . . But neither Oppenheimer nor others seriously developed the idea before it was taken up by Dirac at the beginning of 1938. Although Dirac's theory was a classical one, very much in the tradition of Lorentz, Poincaré, and Abraham, it was clearly motivated by his wish to solve the divergence problems of quantum electrodynamics. . . . The Dirac electron was, as in earlier works on quantum theory, a point electron. . . . In accordance with his general view of physics, he did not attempt to build up a new model of the electron but tried to 'get a simple scheme of equations which can be used to calculate all the results that can be obtained from experiment' [p. 149]. It was always Dirac's ideal, in formulating a physical theory, to be able to work out a 'reasonable mathematical scheme' and then interpret the equations in the most direct and natural way. . . . The first occasion on which Dirac explained his new theory of classical electrons was in a talk given to the . . . Club, probably in March 1938. . . . It was the secretary's duty to find speakers, and [Fred] Hoyle phoned Dirac to persuade him to give a talk. 'When he had understood my request,' Hoyle recalled, 'Dirac made a remark which nobody else in my experience would have conceived of: "I will put down the telephone for a minute and think, and then speak again," he said' " (Kragh, Dirac, a Scientific Biography, pp. 189, 191, 195). Kragh (1938b). Paul Dirac shared the Nobel Prize in Physics in 1933 with Erwin Schrödinger "for the discovery of new productive forms of atomic theory."
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Seventy Noteworthy Medical Rarities (Several of Medico-Literary Interest) in Honor of the Seventieth Birthday of Dr. Harvey Cushing. Together with a Tribute by Dr. Lawrence Reynolds.

Frontispiece [of Harvey Cushing], 47, [1, ad for the journal Isis] pp; plates. Cloth, with original printed wrappers bound in. Cloth covers warped. Vertical crease in wrappers and pages of the catalogue. Ink check margin in margin of p. 7 (by item 1). Good. First Edition. Henry Schuman, Catalogue 5, Autumn 1939. Leaving aside a medieval medical manuscript, the four most expensive books were, in this order from highest price down, two works by Ambroise Paré (1764 and 1768), Robert Boyle's Sceptical Chymist (1661), and Andreas Vesalius's De Humani Corporis Fabrica (1543), ranging from $775 to $550. In the July 21, 1941, issue of Time magazine, there is an article about the bookseller Henry Schuman, with a reference to Harvey Cushing as his "star customer": "A specialist who caters to a profession of specialists is Bookseller Henry Schuman, dealer in rare medical books. Mr. Schuman has made a very good thing out of what started as a hobby. Last week he moved ten tons (about 20,000 volumes) of valuable books to his new, five-story house-and-bookshop on Manhattan's swank East 70th Street. Nine years ago, as a young businessman in Detroit, Henry Schuman opened a little bookshop with his collection of first editions. One day an elderly doctor wandered in, asked for a volume by Réné Laennec, inventor of the stethoscope (1819). Bookseller Schuman found the search for this book as exciting as 'digging in the Klondike,' turned up several unexpected medical treasures along the way. After this, he devoted himself to rare medical books. Mr. Schuman has tracked down books for almost every medical bibliophile in the U.S. His star customer was the late Neurologist Harvey Cushing, whose famed medical collection was recently installed in the new Yale Medical Library. Dr. Cushing longed for the first medical book ever published in the American colonies--a copy of a lurid best-seller on herbalism which had been written in England by one Nicholas Culpeper (Boston, 1708). But he never got his hands on one of these first editions. No less than three first editions of medicine's great classic--De Motu Cordis, by William Harvey (1578-1657), discoverer of the circulation of the blood, have passed through Mr. Schuman's hands. About 17 first editions of this work are extant. The third copy, worth several thousand dollars, Mr. Schuman found in Los Angeles. Its owner, a confirmed invalid, was lying in bed drinking whiskey, flanked by a bar and a vault of rare book's. Reprints of medical articles announcing great modern discoveries are as rare and valuable as 15th-Century incunabula. One of the rarest items Mr. Schuman ever handled was a reprint of Dr. Oliver Wendell Holmes's brief essay proving that childbed fever may be caused by filthy obstetricians and hospital wards. Several years ago, Mr. Schuman visited the late Sir Frederick Banting in Toronto, asked him to sell a reprint of his first article on the discovery of insulin. Replied Sir Frederick ruefully: 'I have only one copy left on file'."
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Tropical Medicine at Harvard: The Weller Years, 1954-1981. A Personal Memoir. SIGNED BY ELI CHERNIN TO NOBEL LAUREATE THOMAS WELLER.

95 pp; illustrations. Original wrappers. The text block has come unglued from the wrappers. It can easily be reglued back into the wrappers, but for now I am leaving it the way it is. This probably happened because of all the items Weller stuffed into the book. First Edition. SIGNED BY ELI CHERNIN TO THOMAS WELLER: "To Tom Weller-/ with my admiration, respect, and affection./ On his 70th birthday,/ Eli Chernin/ 16 June 1985". Eli Chernin (1924-1990) was a Professor of Tropical Medicine in the Harvard School of Public Health and a colleague of Thomas Weller at Harvard from 1954-1981, the "Weller Years" of the title. A number of photographs of Thomas Weller have been reproduced on pp. 17-24. The book is offered with several original, or photocopied, letters relating to the book, as well as photocopied reviews of the book (photos of all the letters are available upon request). In his autobiography "Growing Pathogens in Tissue Cultures, Fifty Years in Academic Tropical Medicine, Pediatrics, and Virology" (2004), Thomas Weller writes about Eli Chernin: "There is no greater responsbility for a departmental chair than to develop an outstanding faculty. It was my privilege to recruit an outstanding team. At the outset of my tenure in 1954, the Department consisted of me and three senior colleagues. . . . [one of the three was] Eli Chernin, a medical and experimental parasitologist, who was my first new recruit to the Department" (p. 185). Weller also wrote about Chernin: "Ludlow Manufacturing and Sales Compnay . . . wanted a parasitological survey done of its work force. Since there was no one available to undertake the job, Eli Chernin, who had just received his doctoral degree in parasitology at Johns Hopkins, was appointed a research associate and assigned to India for a year. After his return . . ., he began to work with me evenings at the Children's [Hospital] studying the growth of Toxoplasma gondii in tissue cultures. . . . I was impressed with Chernin's diligence and investigative interests" (p. 182). John Enders, Thomas Weller, and Frederick Robbins were awarded the Nobel Prize in Physiology or Medicine in 1954 "for their discovery of the ability of poliomyelitis viruses to grow in cultures of various types of tissue."
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Medicine in Modern Times or Discoveries Delivered at a Meeting of the British Medical Association at Oxford by Dr. Stokes, Dr. Acland, Professor Rolleston, Rev. Professor Haughton, and Dr. Gull, with a Report on Mercury by Dr. Hughes Bennett.

vii, 255 pp; 8 pp of publisher's ads. Original cloth. Spine sunned. Lightly foxed. Near Fine. First Edition. Contents: 1. VALEDICTORY ADDRESS, by W. STOKES; 2. THE GENERAL RELATIONS OF MEDICINE IN MODERN TIMES, by HENRY W. ACLAND; 3. PHYSIOLOGY IN RELATION TO MEDICINE IN MODERN TIMES, by G. ROLLESTON; PHYSICS IN RELATION TO MEDICINE IN MODERN TIMES, illustrated by the relation of food to work, and its bearing on medical practice, by the Rev. SAMUEL HAUGHTON; 5. CLINICAL OBSERVATION IN RELATION TO MEDICINE IN MODERN TIMES, by W. W. GULL; 6. THERAPEUTICAL RESEARCH IN RELATION TO MEDICINE IN MODERN TIMES, as illustrated by researches into the action of Mercury on the biliary secretion. Report by J. HUGHES BENNETT. Quoting from the Preface (pp. v-vi): "The following Addresses were delivered in Oxford on August 5, 6, and 7 of last year, before the Medical Association of Great Britain and Ireland, several Visitors from foreign Countries, and special Delegates from the United States. The Association consists of more than 4,000 medical men; of these between 500 and 600 attended the Oxford Meeting. The Addresses may serve to show some of the aims of the Association as understood by the several speakers. Although such Essays do not commit the profession to any opinions or objects, they nevertheless are of some public interest as illustrating what in the opinion of several independent thinkers would be likely to be cordially received by their professional brethren on the subjects set before them. A Report, which was not an Address in the ordinary sense, is added, because it was presented to a Special General Meeting, and because it is an example of one method of medical enquiry. The exact value of this method is as little understood by many in the present day, as it may perhaps be overrated by a few. In a sketch of Medicine this kind of investigation could not but be recognized as an important form of modern research."
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The Cutter Incident. How America’s First Polio Vaccine Led to the Growing Vaccine Crisis. SIGNED BY PAUL OFFIT TO NOBEL LAUREATE THOMAS H. WELLER.

OFFIT, Paul A. [WELLER, Thomas H.] xii, 238 pp; illustrations. Original cloth. Near Fine, in dust jacket. First Edition. SIGNED BY PAUL OFFIT TO NOBEL LAUREATE THOMAS H. WELLER: "To Tom,/ Thanks again for all of your insights/ into this tragedy./ I m not sure I could have written/ this book without you./ All best wishes/ Paul A. Offit/ September, 2005." This copy does not have any ownership marking in it, but I know "Tom" is Thomas H. Weller because the book, as well as other items owned by Weller that do have his name written in them, were acquired by me from the family after Weller's death in 2008. The Nobel Prize in Physiology or Medicine 1954 was awarded jointly to John Franklin Enders, Thomas Huckle Weller and Frederick Chapman Robbins "for their discovery of the ability of poliomyelitis viruses to grow in cultures of various types of tissue." In the book on pp. 80 and 130, Offit quotes Weller's negative views, which were shared by others who are also quoted by Offit, that Jonas Salk was not a good scientist, never having been elected to the National Academy of Sciences nor awarded the Nobel Prize. However Offit expresses his own contrary view that "although not appreciated by many scientists, Salk made several important conceptual and technological advances that led to one of the greatest public heath achievements of our time" (p. 131). As a footnote, I would note that Salk, and Stephen Hawking, are probably the two persons most cited by the media as having received a Nobel Prize who did NOT receive the Prize. Quoting Wikipedia about the "Cutter Incident": "On April 12, 1955, following the announcement of the success of the polio vaccine trial, Cutter Laboratories became one of several companies that was recommended to be given a license by the United States government to produce Salk's polio vaccine. In anticipation of the demand for vaccine, the companies had already produced stocks of the vaccine and these were issued once the licenses were signed. In what became known as the Cutter incident, some lots of the Cutter vaccine--despite passing required safety tests--contained live polio virus in what was supposed to be an inactivated-virus vaccine. Cutter withdrew its vaccine from the market on April 27 after vaccine-associated cases were reported. The mistake produced 120,000 doses of polio vaccine that contained live polio virus. Of children who received the vaccine, 40,000 developed abortive poliomyelitis (a form of the disease that does not involve the central nervous system), 56 developed paralytic poliomyelitis--and of these, five children died from polio. The exposures led to an epidemic of polio in the families and communities of the affected children, resulting in a further 113 people paralyzed and 5 deaths. The director of the microbiology institute lost his job, as did the equivalent of the assistant secretary for health. Secretary of Health, Education, and Welfare Oveta Culp Hobby stepped down. William H. Sebrell Jr, the director of the NIH, resigned."
  • $150
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Cautions to Young Persons Concerning Health, in a Public Lecture Delivered at the Close of the Medical Course in the Chapel at Cambridge, November 20, 1804; Containing the General Doctrine of Dyspepsia and Chronic Diseases; Shewing the Evil Tendency of the Use of Tobacco upon Young Persons; More Especially the Pernicious Effects of Smoking Cigars. With Observations on the Use of Ardent and Vinous Spirits. Fifth Edition with Additional Notes. WITH ORIGINAL PRINTED WRAPPERS.

WATERHOUSE, Benjamin xii, [13]-40 pp. Original printed wrappers, stitched, as issued. Top half of spine missing. Ink stamp of "Boston Medical Library, Jul 12 1934" on front wrapper, on verso of title page and on p. v. Some pages very browned and possibly stained (for example pp. 13, 14, 15, and 40, rear flyleaf, inside of rear wrapper). Gift inscription on front flyleaf, and ink note about this "queer production" (see photo). NOTE ABOUT PHOTOS: I can send more photos, upon request. Fifth Edition, but also the "Second American Edition". The front wrapper has this title printed on it: "Dr. Waterhouse's Public Lecture, on the Pernicious Effects of Smoking Cigars. Fifth Edition." In his "Introduction to this second American edition" (pp. v-xii) Waterhouse describes the five editions of this work: "Seventeen years ago [1805], the Students in the University asked and obtained permission to publish this Lecture 'on the pernicious effects of smoking cigars.' Since then, a new edition has appeared in London; and a French one at Geneva [1807]. A German translation was made and published in the year 1808 at Vienna, by the learned Dr. De Carro. It has been reprinted in detached portions in South Carolina, with comments by the late eminent historian and physician Dr. Ramsay; and several Presidents or Rectors of Colleges, in different States, have caused it to be read in their chapels, as a warning to the young men under their care. This evidence of its utility has induced the author to print a new edition; and to add some letters and a few notes not to be found in the former impressions; all tending to add weight to his cautions to young persons concerning health'." In the biography (2006) of Benjamin Waterhouse by Philip Cash, Dr. Benjamin Waterhouse: A Life in Medicine and Public Service (1754-1846), Cash writes: "Much to his surprise, Waterhouse's tract struck a highly responsive chord among liberal reformers and evangelical Protestants in both the United States and Europe. Between 1805 and 1822, no less than six editions were published: two in the United States and one each in Edinburgh, London, Geneva (in French), and Vienna (in German). In addition, Dr. Ramsay had it republished in a Charleston newspaper. Among others, the work was praised by John Adams, Jefferson, Jenner, Samuel Latham Mitchill, and Rush. In 1807, Waterhouse wrote to [John Coakley] Lettsom: 'I may venture to mention to a friend, that this little publication acquired more popularity than any medical or philosophical publication ever printed in America. It excited the attention of all parents who had sons in College. It was popular with every one who had journeymen, apprentices, or clerks, who were apprehensive of fire from smoking cigars. It was popular with the married ladies, whose husbands were in that habit; and it was violently popular with all the young ones who wished for husbands and hated the smell of tobacco. It was a matter of serious consideration with the clergy, because it called their virtue into question [on pp. 37-38 of this edition Waterhouse discusses smoking by the clergy].' This work greatly broadened Waterhouse's reputation both in America and in Europe. Yet it always aggravated him that this tract 'borne up in the air of fashion', won him greater recognition than his much more important writings on [smallpox] vaccination" (pp. 268-269). The first edition, of 32 pages, was published in 1805 in Cambridge MA. The 1822 edition offered here, of 40 pages, is called the "second American edition" by Waterhouse on p. v. The three other editions, making five editions in all, are the London, Geneva (French), and Vienna (German) editions. Philip Cash mentions six editions, adding one in Edinburgh.
  • $250
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Founders of the Harvard School of Public Health with Biographical Notes 1909-1946. COPY OF NOBEL LAUREATE THOMAS H. WELLER

CURRAN, Jean Alonzo [WELLER, Thomas H.] xviii, 1 leaf, 294 pp; illustrations. Original cloth. Very Good. First Edition. COPY OF NOBEL LAUREATE THOMAS H. WELLER, with his ink signature "T H Weller (gift)" on the front flyleaf. John Enders, Thomas Weller, and Frederick Robbins shared the Nobel Prize in Physiology or Medicine "for their discovery of the ability of poliomyelitis viruses to grow in cultures of various types of tissue." Quoting from the website of the American Association of Immunologists: Weller "was appointed the Richard Pearson Strong Professor and Chair of the Department of Tropical Public Health at the Harvard School of Public Health. He chaired the department for 27 years, stepping down from the position in 1981 and retiring from teaching in 1985, when he was named professor emeritus. Throughout his career, Weller remained active in public health, serving on several committees established to address tropical diseases, including the Commission on Parasitic Diseases of the American Armed Forces Epidemiological Board (1953 59), the World Health Organization Committee on Medical Research (1967 70), the National Advisory Council of the Centers for Disease Control (1968 72), the Pan American Health Organization Advisory Committee on Medical Research (1970 81), and the National Institute of Allergy and Infectious Diseases National Advisory Council (1977 80)." Quoting from the website of the Harvard T. H. Chan School of Public Health: " 'Beyond his pioneering scientific breakthroughs in growing polio in culture and discovering varicella and rubella viruses, all of which made the new vaccines possible, Professor Weller became a champion for public health and the effort to focus the best of science on the diseases and health problems of the poorest people on the globe,' said Barry R. Bloom, Dean of Harvard School of Public Health. 'His impact has been incalculable, and his legacy will be something cherished by generations to come at HSPH and far beyond'. . . . 'Thomas Weller was one of the great scientists of the 20th century and a leader in neglected tropical diseases,' said Dyann Wirth, chair of the HSPH Department of Immunology and Infectious Diseases and Richard Pearson Strong Professor of Infectious Diseases. 'He inspired many during his lifetime, and his vision led an entire field for many decades. His legacy is one to be remembered'. "
  • $75
Mathematische Begründung der Quantenmechanik." Aus den Nachrichten der Gesellschaft der Wissenschaften zu Göttingen. Mathematisch-Physikalische Klasse 1926.

Mathematische Begründung der Quantenmechanik.” Aus den Nachrichten der Gesellschaft der Wissenschaften zu Göttingen. Mathematisch-Physikalische Klasse 1926.

NEUMANN, J. v. [John von] 57 pp. Original printed wrappers, rebacked with new paper spine. Wrappers extensively remargined. Good. NOTE ABOUT PHOTOS: ABEBooks allows only 5 photos. I think these photos convey the extent of the restoration on this copy, but I can supply more photos of the restored wrappers, upon request. First Separate Printing. Pencil corrections in the text on pp. 27 and 45. I don't pretend to understand the following quotations, but they come from authoritative sources. Von Neumann "developed between 1927 [the paper offered here] and 1929 a new mathematical framework of the theory which subsequently proved to be the most suitable formalism of nonrelativistic quantum mechanics as we use it today [1966], as well as of its extensions, the relativistic quantum mechanics of particles and the quantum theory of fields" (Max Jammer, The Conceptual Development of Quantum Mechanics, pp. 314-315. "Von Neumann's most famous work in theoretical physics is his axiomatization of quantum mechanics. When he began work in that field in 1927 [in the paper offered here], the methods used by its founders were hard to formulate in precise mathematical terms: 'operators' on 'functions' were handled without much consideration of their domain of definition or their topological properties and it was blithely assumed that such 'operators,' when self-adjoint, could always be 'diagonalized' (as in the finite dimensional case), at the expense of introducing 'Dirac functions' as 'eigenvectors'. Von Neumann showed that mathematical rigor could be restored by taking as basic axioms the assumptions that the states of a physical system were points of a Hilbert space and that the measurable quantities were Hermitian (generally unbounded) operators densely defined in that space. This formalism, the practical use of which became available after von Neumann had developed the spectral theory of unbounded Hermitian operators (1929), has survived subsequent developments of quantum mechanics and is still the basis of non relativistic quantum theory; with the introduction of the theory of distributions, it has even become possible to interpret its results in a way similar to Dirac's original intuition" (J. Dieudonné, in D.S.B. 14: 91). The D.S.B. is the Dictionary of Scientific Biography, a magnificent reference work in 18 volumes.
  • $1,750
  • $1,750
Autograph Letter

Autograph Letter, Signed, from Charles Best to “all the children in Mr. Bean’s class”, November 15, 1972.

BEST, Charles 2 leaves. Very Good. Letterhead: Banting and Best Department of Medical Research, Charles H. Best Institute, University of Toronto, Toronto 101, Canada. Charles Best thanks the children in Mr. Bean's class in Saco, Maine, for their holiday greetings and for sending him "your card, drawing, gifts, and clippings about the Field Day at Saco." Best advises the children "that it pays to do one's very best whether in sports or in anything we undertake. Listen carefully to all the things Mr. Bean talks about and almost unconsciously you will learn new facts every day. That is something we should all do, no matter what our age." Best is sending the children "a special card to wish each of you a very happy vacation. This card shows you a painting I did of Schooner Cove where we often spend our summers and this makes us almost neighbours because Schooner Cove is in the State of Maine too although at the northern tip while Saco is at the south." Charles Best's parents were Canadian, but Best was born in northern Maine, near the Maine-New Brunswick border, where his father had his medical practice. Best grew up in Maine before he went to the University of Toronto in 1915. I have no information as to what led the children in Mr. Bean's class in Saco, Maine, to write to Best in 1972. A guess might be that Mr. Bean taught the children about insulin and diabetes and that is what led them to write to Best. The Nobel Prize for Physiology and Medicine in 1923 was awarded jointly to Frederick Grant Banting and John James Rickard Macleod "for the discovery of insulin". Banting had done his research on diabetes and insulin in collaboration with Charles Best. Banting believed that Best should also have received the Nobel Prize, and so Banting shared with Best the money Banting had received with his Nobel Prize. "Best was not awarded a Nobel Prize. However, he did have the satisfaction of knowing that the 1972 official history of the Nobel Prize acknowledged that a mistake had been made in 1923. 'Although it would have been right to include Best among the prize-winners, this was not formally possible, since no one had nominated him--a circumstance which probably gave the Committee a wrong impression of the importance of Best's share in the discovery' " (quoted in Louis Rosenfeld, "Insulin: Discovery and Controversy", Clinical Chemistry, Volume 48, issue 12, 1 December 2002; this article can be read online for free).
  • $200